PHARMACOLOGICAL ISOLATION OF POSTSYNAPTIC CURRENTS MEDIATED BY NR2A- AND NR2B-CONTAINING NMDA RECEPTORS IN THE ANTERIOR CINGULATE CORTEX

Pharmacological isolation of postsynaptic currents mediated by NR2A- and NR2B-containing NMDA receptors in the anterior cingulate cortex

Abstract NMDA receptors (NMDARs) are involved in excitatory synaptic transmission and plasticity associated with a variety of brain functions, Electrical Tape from memory formation to chronic pain.Subunit-selective antagonists for NMDARs provide powerful tools to dissect NMDAR functions in neuronal activities.Recently developed antagonist for NR2A-

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Convergent synthetic methodology for the construction of self-adjuvanting lipopeptide vaccines using a novel carbohydrate scaffold

A novel convergent synthetic strategy for the construction of multicomponent self-adjuvanting lipopeptide vaccines was developed.A Blazer tetraalkyne-functionalized glucose derivative and lipidated Fmoc-lysine were prepared by novel efficient and convenient syntheses.The carbohydrate building block was coupled to the self-adjuvanting lipidic moiety

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Co-inoculation with rhizobia and AMF inhibited soybean red crown rot: from field study to plant defense-related gene expression analysis.

BackgroundSoybean red crown rot is a major soil-borne disease all over the world, which severely affects soybean production.Efficient and sustainable methods are strongly desired to control the soil-borne diseases.Principal findingsWe firstly investigated the disease incidence and index of soybean red crown rot under different phosphorus (P) additi

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